Sail Central America from Atlantic to Pacific
View natural beauty and an engineering marvel across the Panama Canal
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Featured Panama Canal Cruises
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9 Night Panama Canal & Caribbean
Norwegian Gem - OPEN BAR!
Departing from: Miami, FloridaPorts of Call:- Puerto Plata, Dominican Republic
- Catalina Island (Isla Catalina), Dominican Republic
- Willemstad, Curacao
- Oranjestad, Aruba
- Panama Canal Full Transit
- Panama City (Fuerte Amador), Panama
Sailing Dates:- December 2024
interior from$808$90pernightoceanview from$858$95pernightbalcony from$908$101pernightsuite from$1,138$126pernightAll the Cruise Line Offers & More:Interior from $808($90pernight)3.8 rating out of 5 (2,488 reviews) -
9 Night Panama Canal & Caribbean
Norwegian Gem - OPEN BAR!
Departing from: Panama City (Fuerte Amador), PanamaPorts of Call:- Panama Canal Full Transit
- Puerto Limon, Costa Rica
- Falmouth, Jamaica
- George Town, Grand Cayman
- Cozumel, Mexico
- Great Stirrup Cay (Cruiseline Private Island), Bahamas
- Miami, Florida
Sailing Dates:- December 2024
interior from$883$98pernightoceanview from$903$100pernightbalcony from$962$107pernightsuite from$1,033$115pernightAll the Cruise Line Offers & More:Interior from $883($98pernight)3.8 rating out of 5 (2,488 reviews) -
12 Night Panama Canal with Costa Rica & Caribbean
Emerald Princess
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- Oranjestad, Aruba
- Willemstad, Curacao
- Cartagena, Colombia
- Panama Canal (Partial Transit)
- Colon, Panama
- Puerto Limon, Costa Rica
- Ocho Rios, Jamaica
Sailing Dates:- November 2024
- December 2024
interior from$1,039$87pernightoceanview from$1,115$93pernightbalcony from$1,429$119pernightsuite from$2,650$221pernightAll the Cruise Line Offers & More:Interior from $1,039($87pernight)4 rating out of 5 (1,196 reviews) -
12 Night Panama Canal with Costa Rica & Caribbean
Emerald Princess
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- Oranjestad, Aruba
- Willemstad, Curacao
- Cartagena, Colombia
- Panama Canal (Partial Transit)
- Colon, Panama
- Puerto Limon, Costa Rica
- George Town, Grand Cayman
Sailing Dates:- October 2024
- November 2024
- March 2025
interior from$959$80pernightoceanview from$1,038$87pernightbalcony from$1,959$163pernightsuite from$3,454$288pernightInterior from $959($80pernight)4 rating out of 5 (1,196 reviews) -
8 Night Panama Canal
Carnival Miracle
Departing from: Tampa, FloridaPorts of Call:- Puerto Limon, Costa Rica
- Colon, Panama
- George Town, Grand Cayman
Sailing Dates:- January 2026
- March 2026
interior from$1,029$129pernightoceanview from$1,179$147pernightbalcony from$1,409$176pernightsuite from$2,559$320pernightAll the Cruise Line Offers & More:Interior from $1,029($129pernight)4 rating out of 5 (2,747 reviews) -
16 Night Panama Canal Carnival Journeys - Eastbound
Carnival Spirit
Departing from: Seattle, WashingtonPorts of Call:- Cabo San Lucas, Mexico
- Puntarenas, Costa Rica
- Panama Canal Full Transit
- Cartagena, Colombia
- New Orleans, Louisiana
Sailing Dates:- October 2024
- October 2025
interior from$1,049$66pernightoceanview from$1,169$73pernightbalcony from$1,399$87pernightsuite from$3,999$250pernightInterior from $1,049($66pernight)3.9 rating out of 5 (976 reviews) -
11 Night Panama Canal: Mexico Costa Rica & Belize
Norwegian Gem - OPEN BAR!
Departing from: Miami, FloridaPorts of Call:- George Town, Grand Cayman
- Cartagena, Colombia
- Panama Canal (Partial Transit)
- Colon, Panama
- Puerto Limon, Costa Rica
- Harvest Caye, Belize
- Cozumel, Mexico
Sailing Dates:- November 2024
- January 2025
interior from$1,141$104pernightoceanview from$1,241$113pernightbalcony from$2,262$206pernightsuite from$2,641$240pernightAll the Cruise Line Offers & More:Interior from $1,141($104pernight)3.8 rating out of 5 (2,488 reviews) -
12 Night Panama Canal Sunfarer
Rotterdam
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- Half Moon Cay, Bahamas (Cruiseline Private Island)
- Willemstad, Curacao
- Cartagena, Colombia
- Enter Panama Canal At Cristobal
- Cruise Gatun Lake And Panama Canal
- Cruise Gatun Lake (Inside Panama Canal)
- Exit Panama Canal At Cristobal
- Colon, Panama
- Puerto Limon, Costa Rica
- Montego Bay, Jamaica
Sailing Dates:- December 2024
interior from$1,099$92pernightoceanview from$1,299$108pernightbalcony from$1,499$125pernightsuite from$2,399$200pernightAll the Cruise Line Offers & More:Interior from $1,099($92pernight)4.4 rating out of 5 (247 reviews) -
12 Night Panama Canal Sunfarer
Rotterdam
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- Half Moon Cay, Bahamas (Cruiseline Private Island)
- Willemstad, Curacao
- Cartagena, Colombia
- Panama Canal (Partial Transit)
- Colon, Panama
- Puerto Limon, Costa Rica
- George Town, Grand Cayman
Sailing Dates:- November 2024
interior from$999$83pernightoceanview from$1,249$104pernightbalcony from$1,299$108pernightsuite from$2,629$219pernightAll the Cruise Line Offers & More:Interior from $999($83pernight)4.4 rating out of 5 (247 reviews) -
11 Night Panama Canal: Cartagena & Cozumel
Norwegian Jade - OPEN BAR!
Departing from: Tampa, FloridaPorts of Call:- Key West, Florida
- Cozumel, Mexico
- George Town, Grand Cayman
- Ocho Rios, Jamaica
- Cartagena, Colombia
- Colon, Panama
- Puerto Limon, Costa Rica
- Panama Canal Full Transit
- Panama City, Panama
Sailing Dates:- January 2025
interior from$1,121$102pernightoceanview from$1,321$120pernightbalcony from$2,121$193pernightsuite from$2,471$225pernightAll the Cruise Line Offers & More:Interior from $1,121($102pernight)3.9 rating out of 5 (1,394 reviews) -
9 Night Panama Canal: Aruba & Cartagena
Norwegian Jade - OPEN BAR!
Departing from: Miami, FloridaPorts of Call:- Puerto Plata, Dominican Republic
- Oranjestad, Aruba
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Full Transit
- Panama City, Panama
Sailing Dates:- November 2025
interior from$1,333$148pernightoceanview from$1,634$182pernightbalcony from$2,384$265pernightsuite from$2,583$287pernightInterior from $1,333($148pernight)3.9 rating out of 5 (1,394 reviews) -
12 Night Panama Canal with Costa Rica & Caribbean
Emerald Princess
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- Kralendijk, Bonaire
- Willemstad, Curacao
- Cartagena, Colombia
- Panama Canal (Partial Transit)
- Colon, Panama
- Puerto Limon, Costa Rica
- George Town, Grand Cayman
Sailing Dates:- February 2025
interior from$1,348$112pernightoceanview from$1,469$122pernightbalcony from$2,498$208pernightsuite from$3,395$283pernightAll the Cruise Line Offers & More:Interior from $1,348($112pernight)4 rating out of 5 (1,196 reviews) -
12 Night Panama Canal with Costa Rica & Caribbean
Caribbean Princess
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- George Town, Grand Cayman
- Falmouth, Jamaica
- Puerto Limon, Costa Rica
- Panama Canal (Partial Transit)
- Colon, Panama
- Oranjestad, Aruba
- Willemstad, Curacao
Sailing Dates:- November 2025
- February 2026
interior from$1,369$114pernightoceanview from$1,407$117pernightbalcony from$2,119$177pernightsuite from$2,619$218pernightAll the Cruise Line Offers & More:Interior from $1,369($114pernight)3.9 rating out of 5 (1,891 reviews) -
16 Night Panama Canal Westward
Serenade of the Seas
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- George Town, Grand Cayman
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Full Transit
- Puerto Quetzal, Guatemala
- Puerto Vallarta, Mexico
- Cabo San Lucas, Mexico
- San Pedro (Los Angeles), California
Sailing Dates:- April 2025
interior from$1,454$91pernightoceanview from$1,885$118pernightbalcony from$2,937$184pernightsuite fromCall for availabilityAll the Cruise Line Offers & More:Was $2,494 – Save up to 42%Interior from $1,454($91pernight)4.1 rating out of 5 (1,790 reviews) -
10 Night Panama Canal: Cartagena & Cozumel
Norwegian Jade - OPEN BAR!
Departing from: Panama City, PanamaPorts of Call:- Panama Canal Full Transit
- Cartagena, Colombia
- Ocho Rios, Jamaica
- George Town, Grand Cayman
- Roatan (Isla Roatan), Bay Islands, Honduras
- Harvest Caye, Belize
- Cozumel, Mexico
- Miami, Florida
Sailing Dates:- November 2025
interior from$1,520$152pernightoceanview from$1,820$182pernightbalcony from$2,620$262pernightsuite from$2,870$287pernightInterior from $1,520($152pernight)3.9 rating out of 5 (1,394 reviews) -
11 Night Panama Canal & Southern Caribbean
Celebrity Beyond
Departing from: Ft. Lauderdale (Port Everglades), FloridaPorts of Call:- Cartagena, Colombia
- Panama Canal (Partial Transit)
- Colon, Panama
- Oranjestad, Aruba
- Kralendijk, Bonaire
- George Town, Grand Cayman
Sailing Dates:- December 2024
interior from$1,390$126pernightoceanview from$1,831$166pernightbalcony fromCall for availabilitysuite from$4,311$392pernightAll the Cruise Line Offers & More:Interior from $1,390($126pernight)4.5 rating out of 5 (251 reviews) -
15 Night Panama Canal - Westbound
Radiance of the Seas
Departing from: Tampa, FloridaPorts of Call:- George Town, Grand Cayman
- Cartagena, Colombia
- Colon, Panama
- Panama Canal Full Transit
- Puerto Quetzal, Guatemala
- Puerto Vallarta, Mexico
- Los Angeles, California
Sailing Dates:- April 2025
interior from$1,679$112pernightoceanview from$1,815$121pernightbalcony from$2,986$199pernightsuite fromCall for availabilityAll the Cruise Line Offers & More:Interior from $1,679($112pernight)4.2 rating out of 5 (1,260 reviews)
Discount Panama Canal Cruises
Search Panama Canal Cruises
- Azamara Cruises from $1,329
- Celebrity Cruises from $1,390
- Cunard from $2,499
- Holland America Line from $999
- Norwegian Cruise Line from $808
- Oceania Cruises from $1,899
- Ponant from $6,420
- Princess Cruises from $959
- Regent Seven Seas Cruises from $8,499
- Royal Caribbean from $1,454
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