Panama Canal Cruises

Sail Central America from Atlantic to Pacific

View natural beauty and an engineering marvel across the Panama Canal

Combine Cruise Line Offers With Our Cruises.com Exclusives
  • You May Qualify for One or More Panama Canal / Central America Cruises Offers
Recommended Panama Canal Cruises

Featured Panama Canal Cruises

Experience the trip of a lifetime as you navigate the 50-mile Panama Canal onboard a cheap Panama Canal cruise, including one of these highly-rated Panama Canal cruises:
  • Norwegian Gem
    3.8 rating out of 5  (2,488 reviews)

    9 Night Panama Canal & Caribbean

    Norwegian Gem - OPEN BAR!

    Departing from: Miami, Florida
    Ports of Call:
    • Puerto Plata, Dominican Republic
    • Catalina Island (Isla Catalina), Dominican Republic
    • Willemstad, Curacao
    • Oranjestad, Aruba
    • Panama Canal Full Transit
    • Panama City (Fuerte Amador), Panama
    Sailing Dates:
    • December 2024
    interior from
    $808
    $90pernight
    oceanview from
    $858
    $95pernight
    balcony from
    $908
    $101pernight
    suite from
    $1,138
    $126pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $400 to Spend on Board
    • Reduced Fares for Third & Fourth Guests
     
    Interior from $808
    ($90pernight)
    3.8 rating out of 5  (2,488 reviews)
  • Norwegian Gem
    3.8 rating out of 5  (2,488 reviews)

    9 Night Panama Canal & Caribbean

    Norwegian Gem - OPEN BAR!

    Departing from: Panama City (Fuerte Amador), Panama
    Ports of Call:
    • Panama Canal Full Transit
    • Puerto Limon, Costa Rica
    • Falmouth, Jamaica
    • George Town, Grand Cayman
    • Cozumel, Mexico
    • Great Stirrup Cay (Cruiseline Private Island), Bahamas
    • Miami, Florida
    Sailing Dates:
    • December 2024
    interior from
    $883
    $98pernight
    oceanview from
    $903
    $100pernight
    balcony from
    $962
    $107pernight
    suite from
    $1,033
    $115pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $400 to Spend on Board
    • Reduced Fares for Third & Fourth Guests
     
    Interior from $883
    ($98pernight)
    3.8 rating out of 5  (2,488 reviews)
  • Emerald Princess
    4 rating out of 5  (1,196 reviews)

    12 Night Panama Canal with Costa Rica & Caribbean

    Emerald Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Oranjestad, Aruba
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • Ocho Rios, Jamaica
    Sailing Dates:
    • November 2024
    • December 2024
    interior from
    $1,039
    $87pernight
    oceanview from
    $1,115
    $93pernight
    balcony from
    $1,429
    $119pernight
    suite from
    $2,650
    $221pernight
    All the Cruise Line Offers & More:
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,039
    ($87pernight)
    4 rating out of 5  (1,196 reviews)
  • Emerald Princess
    4 rating out of 5  (1,196 reviews)

    12 Night Panama Canal with Costa Rica & Caribbean

    Emerald Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Oranjestad, Aruba
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • George Town, Grand Cayman
    Sailing Dates:
    • October 2024
    • November 2024
    • March 2025
    interior from
    $959
    $80pernight
    oceanview from
    $1,038
    $87pernight
    balcony from
    $1,959
    $163pernight
    suite from
    $3,454
    $288pernight
    All the Cruise Line Offers & More:
    • Exclusive Last-Minute Bonus: Up to a $100 Reward
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $959
    ($80pernight)
    4 rating out of 5  (1,196 reviews)
  • Carnival Miracle
    4 rating out of 5  (2,747 reviews)

    8 Night Panama Canal

    Carnival Miracle

    Departing from: Tampa, Florida
    Ports of Call:
    • Puerto Limon, Costa Rica
    • Colon, Panama
    • George Town, Grand Cayman
    Sailing Dates:
    • January 2026
    • March 2026
    interior from
    $1,029
    $129pernight
    oceanview from
    $1,179
    $147pernight
    balcony from
    $1,409
    $176pernight
    suite from
    $2,559
    $320pernight
    All the Cruise Line Offers & More:
    • VIFP Members: Unlock big savings!
    • Exclusive: Up to $75 to Spend on Board
    • Up to 4-Category Upgrade!
     
    Interior from $1,029
    ($129pernight)
    4 rating out of 5  (2,747 reviews)
  • Carnival Spirit
    3.9 rating out of 5  (976 reviews)

    16 Night Panama Canal Carnival Journeys - Eastbound

    Carnival Spirit

    Departing from: Seattle, Washington
    Ports of Call:
    • Cabo San Lucas, Mexico
    • Puntarenas, Costa Rica
    • Panama Canal Full Transit
    • Cartagena, Colombia
    • New Orleans, Louisiana
    Sailing Dates:
    • October 2024
    • October 2025
    interior from
    $1,049
    $66pernight
    oceanview from
    $1,169
    $73pernight
    balcony from
    $1,399
    $87pernight
    suite from
    $3,999
    $250pernight
    All the Cruise Line Offers & More:
    • VIFP Members: Unlock big savings!
    • Exclusive Last-Minute Bonus: Up to a $100 Reward
    • Exclusive: Up to $75 to Spend on Board
    • Great Rates + Free Room Upgrade
    • Up to 4-Category Upgrade!
     
    Interior from $1,049
    ($66pernight)
    3.9 rating out of 5  (976 reviews)
  • Norwegian Gem
    3.8 rating out of 5  (2,488 reviews)

    11 Night Panama Canal: Mexico Costa Rica & Belize

    Norwegian Gem - OPEN BAR!

    Departing from: Miami, Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • Harvest Caye, Belize
    • Cozumel, Mexico
    Sailing Dates:
    • November 2024
    • January 2025
    interior from
    $1,141
    $104pernight
    oceanview from
    $1,241
    $113pernight
    balcony from
    $2,262
    $206pernight
    suite from
    $2,641
    $240pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $400 to Spend on Board
    • 3rd & 4th Guests Sail Free!
    • 70% off 2nd Guest + Enhanced More at Sea Perks
     
    Interior from $1,141
    ($104pernight)
    3.8 rating out of 5  (2,488 reviews)
  • Rotterdam
    4.4 rating out of 5  (247 reviews)

    12 Night Panama Canal Sunfarer

    Rotterdam

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Half Moon Cay, Bahamas (Cruiseline Private Island)
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Enter Panama Canal At Cristobal
    • Cruise Gatun Lake And Panama Canal
    • Cruise Gatun Lake (Inside Panama Canal)
    • Exit Panama Canal At Cristobal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • Montego Bay, Jamaica
    Sailing Dates:
    • December 2024
    interior from
    $1,099
    $92pernight
    oceanview from
    $1,299
    $108pernight
    balcony from
    $1,499
    $125pernight
    suite from
    $2,399
    $200pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $300 to Spend on Board - Call
    • One Week Sale: Up to 45% Off!
    • Free Drinks, Dining, and Excursions with Select Fares
     
    Interior from $1,099
    ($92pernight)
    4.4 rating out of 5  (247 reviews)
  • Rotterdam
    4.4 rating out of 5  (247 reviews)

    12 Night Panama Canal Sunfarer

    Rotterdam

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Half Moon Cay, Bahamas (Cruiseline Private Island)
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • George Town, Grand Cayman
    Sailing Dates:
    • November 2024
    interior from
    $999
    $83pernight
    oceanview from
    $1,249
    $104pernight
    balcony from
    $1,299
    $108pernight
    suite from
    $2,629
    $219pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $300 to Spend on Board - Call
    • Free Drinks, Dining, and Excursions with Select Fares
     
    Interior from $999
    ($83pernight)
    4.4 rating out of 5  (247 reviews)
  • Norwegian Jade
    3.9 rating out of 5  (1,394 reviews)

    11 Night Panama Canal: Cartagena & Cozumel

    Norwegian Jade - OPEN BAR!

    Departing from: Tampa, Florida
    Ports of Call:
    • Key West, Florida
    • Cozumel, Mexico
    • George Town, Grand Cayman
    • Ocho Rios, Jamaica
    • Cartagena, Colombia
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • Panama Canal Full Transit
    • Panama City, Panama
    Sailing Dates:
    • January 2025
    interior from
    $1,121
    $102pernight
    oceanview from
    $1,321
    $120pernight
    balcony from
    $2,121
    $193pernight
    suite from
    $2,471
    $225pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $400 to Spend on Board
    • Second Guest Flies Free
    • Reduced Fares for Third & Fourth Guests
    • 70% off 2nd Guest + Enhanced More at Sea Perks
     
    Interior from $1,121
    ($102pernight)
    3.9 rating out of 5  (1,394 reviews)
  • Norwegian Jade
    3.9 rating out of 5  (1,394 reviews)

    9 Night Panama Canal: Aruba & Cartagena

    Norwegian Jade - OPEN BAR!

    Departing from: Miami, Florida
    Ports of Call:
    • Puerto Plata, Dominican Republic
    • Oranjestad, Aruba
    • Cartagena, Colombia
    • Colon, Panama
    • Panama Canal Full Transit
    • Panama City, Panama
    Sailing Dates:
    • November 2025
    interior from
    $1,333
    $148pernight
    oceanview from
    $1,634
    $182pernight
    balcony from
    $2,384
    $265pernight
    suite from
    $2,583
    $287pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $400 to Spend on Board
    • Save up to $250 Instantly! Call and Mention: CruiseFirst
    • Second Guest Flies Free
    • 70% off 2nd Guest + Enhanced More at Sea Perks
     
    Interior from $1,333
    ($148pernight)
    3.9 rating out of 5  (1,394 reviews)
  • Emerald Princess
    4 rating out of 5  (1,196 reviews)

    12 Night Panama Canal with Costa Rica & Caribbean

    Emerald Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Kralendijk, Bonaire
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • George Town, Grand Cayman
    Sailing Dates:
    • February 2025
    interior from
    $1,348
    $112pernight
    oceanview from
    $1,469
    $122pernight
    balcony from
    $2,498
    $208pernight
    suite from
    $3,395
    $283pernight
    All the Cruise Line Offers & More:
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,348
    ($112pernight)
    4 rating out of 5  (1,196 reviews)
  • Caribbean Princess
    3.9 rating out of 5  (1,891 reviews)

    12 Night Panama Canal with Costa Rica & Caribbean

    Caribbean Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Falmouth, Jamaica
    • Puerto Limon, Costa Rica
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Oranjestad, Aruba
    • Willemstad, Curacao
    Sailing Dates:
    • November 2025
    • February 2026
    interior from
    $1,369
    $114pernight
    oceanview from
    $1,407
    $117pernight
    balcony from
    $2,119
    $177pernight
    suite from
    $2,619
    $218pernight
    All the Cruise Line Offers & More:
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • Here Comes the Sun Sale: Save up to 40%
     
    Interior from $1,369
    ($114pernight)
    3.9 rating out of 5  (1,891 reviews)
  • Serenade of the Seas
    4.1 rating out of 5  (1,790 reviews)

    16 Night Panama Canal Westward

    Serenade of the Seas

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Cartagena, Colombia
    • Colon, Panama
    • Panama Canal Full Transit
    • Puerto Quetzal, Guatemala
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • San Pedro (Los Angeles), California
    Sailing Dates:
    • April 2025
    interior from
    $1,454
    $91pernight
    oceanview from
    $1,885
    $118pernight
    balcony from
    $2,937
    $184pernight
    suite from
    Call for availability
    All the Cruise Line Offers & More:
    • 60% Off Second Guest
    • Weekend Flash Sale: Up to $600 Instant Savings
     
    Was $2,494 – Save up to 42%
    Interior from $1,454
    ($91pernight)
    4.1 rating out of 5  (1,790 reviews)
  • Norwegian Jade
    3.9 rating out of 5  (1,394 reviews)

    10 Night Panama Canal: Cartagena & Cozumel

    Norwegian Jade - OPEN BAR!

    Departing from: Panama City, Panama
    Ports of Call:
    • Panama Canal Full Transit
    • Cartagena, Colombia
    • Ocho Rios, Jamaica
    • George Town, Grand Cayman
    • Roatan (Isla Roatan), Bay Islands, Honduras
    • Harvest Caye, Belize
    • Cozumel, Mexico
    • Miami, Florida
    Sailing Dates:
    • November 2025
    interior from
    $1,520
    $152pernight
    oceanview from
    $1,820
    $182pernight
    balcony from
    $2,620
    $262pernight
    suite from
    $2,870
    $287pernight
    All the Cruise Line Offers & More:
    • Exclusive: Up to $400 to Spend on Board
    • Save up to $250 Instantly! Call and Mention: CruiseFirst
    • Second Guest Flies Free
    • 70% off 2nd Guest + Enhanced More at Sea Perks
     
    Interior from $1,520
    ($152pernight)
    3.9 rating out of 5  (1,394 reviews)
  • Celebrity Beyond
    4.5 rating out of 5  (251 reviews)

    11 Night Panama Canal & Southern Caribbean

    Celebrity Beyond

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Oranjestad, Aruba
    • Kralendijk, Bonaire
    • George Town, Grand Cayman
    Sailing Dates:
    • December 2024
    interior from
    $1,390
    $126pernight
    oceanview from
    $1,831
    $166pernight
    balcony from
    Call for availability
    suite from
    $4,311
    $392pernight
    All the Cruise Line Offers & More:
    • All-Included: Free Drinks & Wi-Fi
    • Exciting Deals: Limited-Time Reduced Rates - Ends Monday!
     
    Interior from $1,390
    ($126pernight)
    4.5 rating out of 5  (251 reviews)
  • Radiance of the Seas
    4.2 rating out of 5  (1,260 reviews)

    15 Night Panama Canal - Westbound

    Radiance of the Seas

    Departing from: Tampa, Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Cartagena, Colombia
    • Colon, Panama
    • Panama Canal Full Transit
    • Puerto Quetzal, Guatemala
    • Puerto Vallarta, Mexico
    • Los Angeles, California
    Sailing Dates:
    • April 2025
    interior from
    $1,679
    $112pernight
    oceanview from
    $1,815
    $121pernight
    balcony from
    $2,986
    $199pernight
    suite from
    Call for availability
    All the Cruise Line Offers & More:
    • 60% Off Second Guest
    • Weekend Flash Sale: Up to $600 Instant Savings
     
    Interior from $1,679
    ($112pernight)
    4.2 rating out of 5  (1,260 reviews)

Discount Panama Canal Cruises

Enjoy exceptional value when you book discount Panama Canal cruises on one of the world's top cruise lines with Cruises.com. Act now for these Panama Canal cruise deals and sail away with bonus offers such as free spending, free upgrades and more. Plus, discount Panama Canal cruises include all meals, accommodations, and countless onboard activities. Discount Panama Canal cruises and discount Carnival cruises are the way to save — plan your cruise vacation of a lifetime before these Panama Canal cruise deals are gone!

Search Panama Canal Cruises